| ADAPT | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Numerical Control | ⊕ United States | Subset of APT |
| APACHE | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Analog | ⊕ Italy | Analog simulation language |
| APT III | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Numerical Control | ⊕ United States | Automatically Programmed Tools v3 |
| BLODI | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Expression oriented | ⊕ United States | BLOck DIagram |
| BMD | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Statistical | ⊕ United States | Bio-Medical statistical language |
| CL-II | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Grammar and Syntax-oriented | ⊕ United States | Compiler generator language |
| COGO | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ 2d shape | ⊕ United States | CO-ordinate GeOmetry system |
| CTSS | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Command systems | ⊕ United States | Command language for CTSS |
| DYSAC | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Difference Equations | ⊕ United States | Continuous simulation system |
| GASP | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Event scheduling | ⊕ United States | General Activity Simulation Program |
| ICES | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Civil | ⊕ United States | Integrated Civil Engineering System |
| L-hat | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Information algebra | ⊕ United States | SHARE Information Algebra |
| MADCAP III | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Multiline | ⊕ United States | Version 3 of Madcap |
| MOD IV | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Expression oriented | ⊕ United States | Digital differential analyzer simulator |
| NUCOM | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Numerical Control | ⊕ United States | CNC language |
| Oettinger's shape language | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ United States | ||
| ROHR Numerical Tool Control | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Numerical Control | ⊕ United States | Sperry Rand NC |
| SAINT | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Algebraic | ⊕ United States | A program to do formal integration |
| SIMSCRIPT | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Event scheduling | ⊕ United States | Discrete simulations package |
| STRIP | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Scanning and section control | ⊕ United States | NBS image manipulation system |
| Z22 compiler | ⊕ 1961 | ↓ ↑ ⊕ Specialised Languages | ⊕ Macroassemblers | ⊕ Germany | High level macro compiler for Zuse Z22 |