CELLSIM(ID:672/cel004)

Cell population simulation 

for Cell Simulation

Modeling populations of biological cells.

Donaghey, Houston 1973
Related languages
CELLSIM => CELLSIM II   Evolution of

Samples:
References:
  • Conference on the Applications of Simulation Using GPSS13-14 November 1967 Hilton Hotel, New York, NY view details Abstract: In the field of cell cycle kinetics there have been a number of computer simulation models that have been developed and reported in the literature (1), (2), (3). CELLSIM is a cell kinetics simulation system which is intended to solve these problems. The user interfaces to the system through a simple problem-oriented language which uses the conventions and the vocabulary common to the cell biologist.
  • Ozkul, O.S., and Donaghey, C.E. "A Cell Kinetics Simulation System" The University of Houston RE 1-72, Aug., 1972 view details
  • Donaghey, C. E., "CELLSIM USERS MANUAL", Dept. of Industrial and Systems Engineering, Univ. Houston, Houston, Texas (Aug. 1973). view details
  • Sammet, Jean E. "Roster of Programming Languages for 1973" p147 view details
          in ACM Computing Reviews 15(04) April 1974 view details
  • C.E. Donaghey, "CELLSIM II User's Manual", U Houston (Sep 1975). view details
          in ACM Computing Reviews 15(04) April 1974 view details
  • Donaghey, E. Charles; and Drewinko, Benjamin "A computer simulation program for the study of cellular growth kinetics and its application to the analysis of human lymphoma cells in vitro" Computers and Biomedical Research 8, 2 (April 1975), 118-128. view details Abstract: A computer simulation program (CELLSIM) is described. The simple language and principles and the flexibility of the program allow biologists to simulate a variety of kinetic behaviors of growing cell populations. The program was evaluated on data obtained from a cultured human Iymphoid cell line. Parameters assessed by the model gave values which were almost identical to those determined experimentally.
          in ACM Computing Reviews 15(04) April 1974 view details
  • Evert CF, Palusinski OA "Application of discrete computer modeling to the dynamics of cell populations" Acta Haematol Pol. 1975 Jul-Sep;6(3) pp175-84 view details Abstract: Computer simulation of the dynamics of cell populations is discussed in the paper. Fundamental features of CELLSIM simulation language are described. Acute leukemia cell population model was implemented on a digital computer using CELLSIM. Some of the computer outputs are shown. The results obtained so far are interesting and promissing for further research.
          in ACM Computing Reviews 15(04) April 1974 view details
  • Stubblefield E and Dennis CM "The simulation of thymidine kinase enzyme kinetics in cultured cells using the computer language Cellsim" J Theor Biol, 61(1) Sep 1976 pp171-84 view details
          in ACM Computing Reviews 15(04) April 1974 view details
  • CE Donaghey, B Drewinko, B Barlogie, and E Stubblefield Simulating flow microfluorometry experiments with the computer language cellsim. Biosystems, Dec 1978; 10(4): 339-47. view details
          in ACM Computing Reviews 15(04) April 1974 view details
  • Donaghey, Charles E. "CELLSIM: A digital simulation language for cell kinetic modelling" pp684-697 view details Abstract: The field of cell kinetics relates to the movement and proliferation of cells through their generative cycle, and how this cycle is affected by chemotherapy treatment. CELLSIM is a discrete, digital simulation language for modelling this process. It allows testing of assumptions about cell kinetics and chemotherapy. The language is interpretive, with the interpreter written in FORTRAN, and has been implemented on a wide variety of computer systems. The language features dynamic memory allocation, arithmetic string manipulation, and the capability of generating random variates from nine classic probability distributions. It uses vocabulary and conventions familiar to the cell kinetics scientist, and is now utilized by some who never before used computers in their research.
          in Proceedings of the 1978 annual conference 1978, Washington, D.C., United States view details
  • Sammet, Jean E "Roster of programming languages for 1976-77" pp56-85 view details
          in SIGPLAN Notices 13(11) Nov 1978 view details
  • Tejada, F., Leung, I., and Zubrod, C. G. (1978), Application Of Computer Simulation (CELLSIM) To Experimentally Determined Head And Neck Cancer Kinetics. Proceedings of the Second Annual Meeting of the Cell Kinetics Soc., St. Louis, MO. view details
          in SIGPLAN Notices 13(11) Nov 1978 view details
  • Donaghey CE "Design history of a cell kinetics simulation language" J Med Syst. 1979 3(1-2) pp19-44 view details Abstract: The field of cell kinetics relates to the movement and proliferation of cells through their generative cycle and to how this cycle is affected by chemotherapy treatment. CELLSIM is a discrete, digital simulation language for modeling this process. The language is interpretive, with the interpreter written in FORTRAN. It has been implemented on a wide variety of computer systems. The language features dynamic memory allocation, arithmetic string manipulation, and the capability of generating random variates from a number of probability distributions. The language has continued to evolve as the needs and desires of cancer researchers have been discovered. Its early use was only in experimental environments, but it is now being used to prescribe actual chemotherapy treatments.

          in SIGPLAN Notices 13(11) Nov 1978 view details
  • Zimmerman J, Rotheier J "History and future of the MUMPS in medical computing" Med Inform 4(1) Jan-Mar 1979 pp5-11 view details Abstract: MUMPS is an integrated language and operating system. It was originally developed in the mid 60s, primarily for the interactive manipulation of text-like, hierachical data found so pervasively in medicine. This paper traces the growth in use of MUMPS. Some of the many medical application for which MUMPS is used are discussed, as are the achievements and goals of the MUMPS Users' Group, particularly in facilitating application transfer. The influence of federal funding upon the growth and use of MUMPS is noted. Of particular importance is the federal support of the MUMPS Development Committee in the standardization of MUMPS, and the MUMPS user's Group in promoting MUMPS information and application exchange.
          in SIGPLAN Notices 13(11) Nov 1978 view details